Journal article
Amina Bshaena, Osama H Almajdoub, Rajaa Alshwesh, Entesar Omran, S. Haq, Faisal Ismail
American Journal of Clinical Pathology, Oxford University Press, 2022
American Journal of Clinical Pathology, Oxford University Press, 2022
DOI
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APA
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Bshaena, A., Almajdoub, O. H., Alshwesh, R., Omran, E., Haq, S., & Ismail, F. (2022). Association Between ABO Blood Group System and COVID-19 Severity. American Journal of Clinical Pathology.
Chicago/Turabian
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Bshaena, Amina, Osama H Almajdoub, Rajaa Alshwesh, Entesar Omran, S. Haq, and Faisal Ismail. “Association Between ABO Blood Group System and COVID-19 Severity.” American Journal of Clinical Pathology (2022).
MLA
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Bshaena, Amina, et al. “Association Between ABO Blood Group System and COVID-19 Severity.” American Journal of Clinical Pathology, Oxford University Press, 2022.
BibTeX Click to copy
@article{amina2022a,
title = {Association Between ABO Blood Group System and COVID-19 Severity},
year = {2022},
journal = {American Journal of Clinical Pathology},
publisher = {Oxford University Press},
author = {Bshaena, Amina and Almajdoub, Osama H and Alshwesh, Rajaa and Omran, Entesar and Haq, S. and Ismail, Faisal}
}
Abstract
Abstract Objectives A possible association between blood group systems (ABO and Rh) and coronavirus disease 2019 (COVID-19) severity has recently been investigated by various studies with conflicting results. However, due to variations in the prevalence of the ABO and Rh blood groups in different populations, their association with COVID-19 might be varied as well. Therefore, we conducted this study on Libyan participants to further investigate this association and make population-based data available to the worldwide scientific community. Methods In this case-control study, ABO and Rh blood groups in 419 confirmed COVID-19 cases in Zawia, Libya, and 271 healthy controls were compared using descriptive statistics and χ 2 tests. Results Blood group A was significantly more prevalent in patients with severe COVID-19 (64/125; 51.2%) than in patients with nonsevere COVID-19 (108/294, 36.7%) (P < .034), whereas the O blood group prevalence was higher in nonsevere COVID-19 cases (131/294, 44.5%) compared with severe cases (43/125, 34.4%) (P < .001). Conclusions The results showed a significant association between blood group A and the severity of COVID-19, whereas patients with blood group O showed a low risk of developing severe COVID-19 infection. No significant association was found between Rh and susceptibility/severity of the disease.